Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
snaBAlkanesulfonate monooxygenase; Catalyzes the oxidation of the proline residue of pristinamycin IIB (PIIB) to pristinamycin IIA (PIIA). (277 aa)    
Predicted Functional Partners:
samS
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.724
SPRI_0180
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.624
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
       0.597
SPRI_0179
Putative 5,10-methylenetetrahydrofolate reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family.
       0.597
SPRI_0181
Ribokinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.597
snaC
NADH:FMN oxidoreductase; Provides the reduced form of flavin mononucleotide for the PIIA synthase reaction.
  
  
 0.554
snaQ
Luciferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.533
SPRI_3670
Oxidoreductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.532
SPRI_0184
Transposase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the transposase 2 family.
       0.517
snbA
Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.486
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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