Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pglC2-oxoisovalerate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (346 aa)    
Predicted Functional Partners:
pglB
Pyruvate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 0.999
SPRI_3702
Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.995
SPRI_3719
Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.995
SPRI_7162
Pyruvate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 0.993
SPRI_3704
Pyruvate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 0.990
SPRI_3721
3-methyl-2-oxobutanoate dehydrogenase subunit E1-alpha; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 0.990
SPRI_2599
Alpha-ketoglutarate decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.981
SPRI_3940
Valine dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.943
SPRI_5318
Dihydrolipoamide acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.943
SPRI_1688
Dihydrolipoamide dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.937
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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