Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_0455LysR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (304 aa)    
Predicted Functional Partners:
kbl
2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
  
    0.793
SPRI_3463
LysR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
  
     0.761
SPRI_4204
LysR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
  
     0.748
SPRI_5938
LysR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
  
     0.702
tdh
L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.
       0.663
SPRI_3831
LysR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
  
     0.641
SPRI_1272
LysR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
  
     0.629
SPRI_6875
LysR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
  
     0.560
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.455
SPRI_2155
Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
  
 0.414
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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