Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SPRI_0491Phosphodiesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (172 aa)    
Predicted Functional Partners:
SPRI_2837
Alkyl hydroperoxide reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.708
SPRI_4935
Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
   0.567
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
       0.521
SPRI_3417
Esterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.508
SPRI_1367
Ankyrin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.497
SPRI_4646
HAM1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.497
SPRI_5042
Ankyrin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.497
SPRI_5043
Ankyrin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.497
SPRI_1844
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 
 0.479
SPRI_6881
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.451
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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