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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_0491Phosphodiesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (172 aa)    
Predicted Functional Partners:
SPRI_1367
Ankyrin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.724
SPRI_4646
HAM1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.724
SPRI_5042
Ankyrin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.724
SPRI_5043
Ankyrin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.724
SPRI_2837
Alkyl hydroperoxide reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.612
SPRI_4935
Glycosyl transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
   0.596
SPRI_1299
Serine/arginine repetitive matrix protein 1; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 
 0.595
SPRI_5504
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 
 0.579
SPRI_1192
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 
 0.558
SPRI_0682
Putative integron gene cassette protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 
 0.542
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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