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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_0696Glycoside hydrolase family 15; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (608 aa)    
Predicted Functional Partners:
SPRI_4104
Trehalose phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
  
 0.946
SPRI_2443
Trehalose synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.934
SPRI_1692
Alpha amylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.933
SPRI_4105
Alpha,alpha-trehalose-phosphate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.756
SPRI_0697
RNA polymerase sigma24 factor; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family.
       0.490
SPRI_0698
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.490
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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