Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_0723Pyridine nucleotide-disulfide oxidoreductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (477 aa)    
Predicted Functional Partners:
SPRI_2599
Alpha-ketoglutarate decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.990
SPRI_0301
Branched-chain alpha-keto acid decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.946
SPRI_7052
Branched-chain alpha-keto acid decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.946
SPRI_5318
Dihydrolipoamide acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.876
SPRI_3719
Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.854
SPRI_3702
Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.843
SPRI_0724
Thioredoxin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.801
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.778
gcvH
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.742
SPRI_5159
Alpha-ketoglutarate decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.738
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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