Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_0771Sodium:solute symporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (577 aa)    
Predicted Functional Partners:
SPRI_0770
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.962
SPRI_0772
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.950
SPRI_0774
LytR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.893
SPRI_5699
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.871
SPRI_2076
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.865
SPRI_0773
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.727
SPRI_4427
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.719
SPRI_1311
AsnC family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.530
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.408
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.