Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SPRI_0810Phosphoesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (575 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.876
SPRI_3783
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 0.832
lig
ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
 
 0.815
SPRI_1068
ATP-dependent DNA ligase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.813
SPRI_0779
3'-phosphoesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.782
SPRI_2571
DNA ligase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.782
SPRI_5932
DNA polymerase I; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.713
SPRI_0301
Branched-chain alpha-keto acid decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
   0.712
SPRI_7052
Branched-chain alpha-keto acid decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
   0.712
SPRI_1888
Haloacid dehalogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.709
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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