Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_0983Polyprenyl diphosphate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (361 aa)    
Predicted Functional Partners:
SPRI_0985
Squalene/phytoene synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.988
SPRI_2843
UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.961
SPRI_4998
UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.957
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
 
 0.930
SPRI_0982
Squalene-hopene cyclase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.925
SPRI_6965
Germacradienol synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.925
idi
Isopentenyl-diphosphate delta isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 
 0.917
SPRI_0541
Polyprenyl synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family.
  
  
0.915
SPRI_2627
Polyprenyl diphosphate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family.
  
  
 
0.908
SPRI_0986
Squalene synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.906
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.