close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_0986Squalene synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (306 aa)    
Predicted Functional Partners:
SPRI_0983
Polyprenyl diphosphate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family.
 
 
 0.978
SPRI_0984
Squalene/phytoene dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.953
SPRI_0985
Squalene/phytoene synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
0.943
SPRI_0982
Squalene-hopene cyclase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.929
SPRI_0980
Hopanoid biosynthesis associated radical SAM protein HpnH; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.859
SPRI_0981
1-hydroxy-2-methyl-2-butenyl 4-diphosphate reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.848
SPRI_1260
NADH dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.788
SPRI_0891
C-5 sterol desaturase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.766
SPRI_1984
Phytoene dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.766
SPRI_3814
Multidrug transporter MatE; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 
 0.758
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.