Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_1007Transcription accessory protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (793 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.867
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.867
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 0.830
SPRI_1006
ScaB; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.774
SPRI_1005
SalK; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.702
nnrD
YjeF protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of [...]
   
   0.657
SPRI_5220
Helicase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.657
SPRI_0949
Tetratricopeptide TPR_1 repeat-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.632
SPRI_1002
AraC family transcription regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.595
SPRI_1001
Glutamine amidotransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.593
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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