Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_1189Streptothricin hydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (284 aa)    
Predicted Functional Partners:
nnrD
YjeF protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of [...]
  
    0.634
gpsA
Glycerol-3-phosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
   0.626
SPRI_1190
N-formylglutamate amidohydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.572
SPRI_1188
Glyoxalase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.561
SPRI_0186
PII peptide synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.545
SPRI_7167
PII peptide synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.545
SPRI_3402
Aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
  
 
 0.522
SPRI_1187
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.497
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.485
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
     
 0.439
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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