STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_1233CoA-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (716 aa)    
Predicted Functional Partners:
SPRI_1231
Acetolactate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family.
 
 
   0.954
frc
Formyl-coenzyme A transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate; Belongs to the CoA-transferase III family. Frc subfamily.
 
     0.930
SPRI_1234
MFS transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.909
SPRI_1228
Dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.792
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
     
 0.758
SPRI_1258
2-dehydropantoate 2-reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.704
SPRI_3791
Chromosome-partitioning protein parB; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the ParB family.
      
 0.644
SPRI_3244
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.576
SPRI_1346
NAD-dependent deacetylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.552
SPRI_1583
Aminotransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.543
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.