Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_1252ROK family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (396 aa)    
Predicted Functional Partners:
SPRI_1249
Sugar ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.729
SPRI_1250
ABC transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.
  
  
 0.721
SPRI_1248
Dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.682
SPRI_1247
AP endonuclease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.622
SPRI_2155
Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.576
SPRI_6864
PTS lactose transporter subunit IIC; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.563
SPRI_1255
GntR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.543
fabH
3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
     
 0.530
SPRI_4643
PTS sugar transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.520
SPRI_1251
Sugar ABC transporter ATPase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.478
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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