Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_1270Serine protease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (612 aa)    
Predicted Functional Partners:
SPRI_1271
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.773
SPRI_1268
Metallophosphoesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.765
arc
ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
 0.737
SPRI_1269
ATPase AAA; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.709
SPRI_1283
Lipoprotein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 
 0.648
SPRI_0597
Metallophosphoesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.607
SPRI_1272
LysR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
       0.553
c106_07c
Acyl carrier protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.545
SPRI_7104
Acyl carrier protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.545
SPRI_3488
Thioesterase domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.510
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (32%) [HD]