lig protein (Streptomyces pristinaespiralis)

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Score

lig

ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (512 aa)

Predicted Functional Partners:

ligA

0.975

SPRI_3783

0.962

ligA-2

0.945

ku-2

0.944

ku

0.893

SPRI_2570

0.891

SPRI_0810

0.878

SPRI_1067

0.844

polA

0.844

SPRI_5932

0.775

Your Current Organism:

Streptomyces pristinaespiralis

NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPRI_0810	SPRI_3783	SPRI_0810	SPRI_3783	Phosphoesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.792
SPRI_0810	SPRI_5932	SPRI_0810	SPRI_5932	Phosphoesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	DNA polymerase I; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.891
SPRI_0810	lig	SPRI_0810	SPRI_1282	Phosphoesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.	0.878
SPRI_0810	polA	SPRI_0810	SPRI_5532	Phosphoesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.956
SPRI_1067	ku	SPRI_1067	SPRI_2569	DNA polymerase LigD polymerase subunit; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	DNA repair protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.	0.893
SPRI_1067	ku-2	SPRI_1067	SPRI_6210	DNA polymerase LigD polymerase subunit; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	DNA repair protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.	0.893
SPRI_1067	lig	SPRI_1067	SPRI_1282	DNA polymerase LigD polymerase subunit; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.	0.844
SPRI_2570	ku	SPRI_2570	SPRI_2569	ATP-dependent DNA ligase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	DNA repair protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.	0.987
SPRI_2570	ku-2	SPRI_2570	SPRI_6210	ATP-dependent DNA ligase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	DNA repair protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.	0.875
SPRI_2570	lig	SPRI_2570	SPRI_1282	ATP-dependent DNA ligase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.	0.891
SPRI_2570	ligA	SPRI_2570	SPRI_2379	ATP-dependent DNA ligase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.	0.465
SPRI_3783	SPRI_0810	SPRI_3783	SPRI_0810	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Phosphoesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.792
SPRI_3783	SPRI_5932	SPRI_3783	SPRI_5932	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase I; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.979
SPRI_3783	lig	SPRI_3783	SPRI_1282	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.	0.962
SPRI_3783	polA	SPRI_3783	SPRI_5532	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.995
SPRI_5932	SPRI_0810	SPRI_5932	SPRI_0810	DNA polymerase I; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Phosphoesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.891
SPRI_5932	SPRI_3783	SPRI_5932	SPRI_3783	DNA polymerase I; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.979
SPRI_5932	lig	SPRI_5932	SPRI_1282	DNA polymerase I; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.	0.775
SPRI_5932	polA	SPRI_5932	SPRI_5532	DNA polymerase I; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.647
ku	SPRI_1067	SPRI_2569	SPRI_1067	DNA repair protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.	DNA polymerase LigD polymerase subunit; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.893