STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_1327Adenylosuccinate lyase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (189 aa)    
Predicted Functional Partners:
efp
Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
  
 0.872
SPRI_1328
3-hydroxybutyryl-CoA dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.700
SPRI_1329
Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.700
SPRI_5338
Iron-sulfur cluster assembly accessory protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family.
    
 
 0.566
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
 0.529
SPRI_1326
Phosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.508
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
 
  0.508
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family.
   
 
  0.502
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
  0.499
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
    0.455
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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