Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_1336Phosphatidylserine synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (286 aa)    
Predicted Functional Partners:
psd
Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
 
 
 0.998
SPRI_6171
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
 
 0.959
SPRI_2150
Phosphatidylglycerophosphate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
 
 0.954
SPRI_2241
Phosphatidate cytidylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the CDS family.
    
 0.930
SPRI_3621
Phosphatidate cytidylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
  0.910
SPRI_5717
Phosphoserine phosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.909
SPRI_3829
Hydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.904
SPRI_2926
Threonine dehydratase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
  0.903
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.901
glyA-2
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.901
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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