Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_1349Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (180 aa)    
Predicted Functional Partners:
SPRI_1350
Peptidase M48; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.773
SPRI_1347
methylated-DNA-protein-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
    0.745
SPRI_6059
ATPase AAA; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
   0.683
kptA
Phosphotransferase KptA/Tpt1; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.
 
  
 0.682
SPRI_0727
TIGR02452 family protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.679
SPRI_2219
Protein T24A6.7; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
      0.668
SPRI_4318
ADP-ribosylglycohydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.648
SPRI_1346
NAD-dependent deacetylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.641
SPRI_1348
DNA-3-methyladenine glycosylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.591
rplX
50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
   
   0.585
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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