STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_1392Dioxygenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (450 aa)    
Predicted Functional Partners:
SPRI_1391
Shy6-polyketide cyclase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.640
SPRI_1844
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.640
egtD
Methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
      
 0.632
purD
Phosphoribosylamine--glycine ligase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the GARS family.
   
  
 0.621
SPRI_4537
Lipoprotein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
      
 0.615
SPRI_1393
MFS transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.514
SPRI_5971
LysR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
       0.514
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 
  0.503
SPRI_6280
Protein of unknown function DUF1503; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.468
SPRI_2203
Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.466
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.