Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_1408Peptidase C14; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (355 aa)    
Predicted Functional Partners:
SPRI_1409
Putative transcriptional activator SRCAP-like protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.875
SPRI_1192
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.842
SPRI_5220
Helicase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.842
SPRI_3089
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.765
SPRI_3366
Acetoin utilization protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.741
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.711
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 0.708
SPRI_0949
Tetratricopeptide TPR_1 repeat-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.701
SPRI_2155
Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.700
SPRI_5888
Phosphatidylinositol kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.694
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.