Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_1494Forkhead-associated protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (133 aa)    
Predicted Functional Partners:
SPRI_2599
Alpha-ketoglutarate decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 
 0.882
SPRI_3743
Serine/threonine protein kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 
 0.812
SPRI_5390
Serine/threonine protein kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 
 0.812
SPRI_3709
Serine/threonine protein kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 
 0.810
SPRI_3708
Serine/threonine protein kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 
 0.788
SPRI_1495
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.613
SPRI_6657
Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.530
SPRI_4557
NAD-glutamate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 
 0.509
SPRI_3783
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.505
rbpA
Electron transporter; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
  
     0.494
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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