Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_1619Pyruvate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (575 aa)    
Predicted Functional Partners:
SPRI_2357
Acetolactate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.986
SPRI_3244
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.939
SPRI_2612
Malate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.929
SPRI_4590
Malate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.929
SPRI_1970
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.928
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.922
ackA-2
Hypothetical protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.922
SPRI_2335
Transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.918
SPRI_2468
Pyruvate kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family.
  
 0.918
SPRI_5515
Pyruvate kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family.
  
 0.918
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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