Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_1657Diguanylate cyclase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (445 aa)    
Predicted Functional Partners:
SPRI_1658
Acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.860
SPRI_6817
Dihydroxyacetone kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 
 0.677
SPRI_6818
Dihydroxyacetone kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 
 0.677
SPRI_1660
Nitrite/sulfate reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
     
 0.540
SPRI_1668
Sulfate ABC transporter ATP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.538
SPRI_1661
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.530
SPRI_1662
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
       0.530
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
       0.530
cysD
Sulfate adenylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.530
SPRI_1665
Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
       0.530
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.