STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_1688Dihydrolipoamide dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (469 aa)    
Predicted Functional Partners:
SPRI_2599
Alpha-ketoglutarate decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.999
SPRI_0301
Branched-chain alpha-keto acid decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.998
SPRI_5318
Dihydrolipoamide acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 0.996
SPRI_3719
Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 0.995
SPRI_3702
Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 0.994
gcvH
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
  
 0.988
SPRI_7052
Branched-chain alpha-keto acid decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.983
gcvT
Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine.
 
 0.976
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
 
 0.959
SPRI_3720
2-oxoisovalerate dehydrogenase subunit beta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.948
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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