STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_1747Diaminohydroxyphosphoribosylaminopyrimidine reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (279 aa)    
Predicted Functional Partners:
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.924
SPRI_6118
Riboflavin synthase subunit alpha; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.842
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
 
 0.819
SPRI_1748
ATPase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.785
SPRI_1749
Peroxiredoxin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.758
SPRI_1746
Indole-3-glycerol phosphate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.752
murC
UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
     
 0.737
SPRI_2183
Bifunctional riboflavin kinase/FMN adenylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the ribF family.
  
  
 0.721
SPRI_1744
Methionine sulfoxide reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the MsrB Met sulfoxide reductase family.
       0.694
SPRI_4905
Dihydrofolate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.635
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.