STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_1857F420-dependent oxidoreductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (307 aa)    
Predicted Functional Partners:
SPRI_1856
Homocysteine methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.870
SPRI_1858
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.808
SPRI_1853
Metallophosphoesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.786
SPRI_1854
Methyltransferase type 12; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.786
fbiB
F420-0--gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0.
 
  
 0.756
SPRI_0474
Nitroreductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
   
 0.750
fbiA
2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
 
   
 0.705
SPRI_1859
Nucleotide pyrophosphohydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.702
SPRI_1860
Biotin transporter BioY; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.702
sepF
Cell division protein SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
       0.674
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.