Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
SPRI_1973NIPSNAP family containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (261 aa)    
Predicted Functional Partners:
SPRI_1972
Helix-turn-helix type 11 domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.576
SPRI_5636
LigA protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.545
SPRI_2805
phiRv2 prophage protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.541
SPRI_2595
GCN5 family acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.534
SPRI_5196
Glycosyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.506
SPRI_6209
Deaminase/reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.482
SPRI_1690
GCN5 family acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
    0.470
SPRI_1974
Para-nitrobenzyl esterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the type-B carboxylesterase/lipase family.
       0.466
SPRI_3462
Silent information regulator protein Sir2; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.458
SPRI_6540
N-acetyltransferase GCN5; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
    0.452
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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