Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_2067Peptidase M16; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (451 aa)    
Predicted Functional Partners:
SPRI_2066
Protease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     0.996
SPRI_1260
NADH dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.982
SPRI_3269
NADH-quinone oxidoreductase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
   
 0.892
atpA
F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
   
 0.889
atpH
ATP synthase F0F1 subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
   
 0.884
SPRI_5351
Ubiquinol-cytochrome c reductase cytochrome b subunit; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.822
SPRI_6663
Iron-sulfur binding oxidoreductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.822
SPRI_5350
Ubiquinol-cytochrome C reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.817
SPRI_5575
FeS-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.817
SPRI_4949
Oxidoreductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.813
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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