Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_2143DEAD/DEAH box helicase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (1548 aa)    
Predicted Functional Partners:
SPRI_2144
DNA glycosylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the FPG family.
 
  
 0.965
SPRI_2142
AraC family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.772
SPRI_2140
Branched-chain amino acid transporter AzlD; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.771
SPRI_2141
Branched-chain amino acid ABC transporter permease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.771
SPRI_2145
3-oxoacyl-ACP reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.723
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
   
    0.650
SPRI_4886
DNA glycosylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the FPG family.
  
  
 0.588
SPRI_2138
DUF3046 domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.530
SPRI_2139
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.530
SPRI_4519
3-methyladenine DNA glycosylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.530
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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