Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
SPRI_2144DNA glycosylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the FPG family. (270 aa)    
Predicted Functional Partners:
SPRI_2143
DEAD/DEAH box helicase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.965
SPRI_4886
DNA glycosylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the FPG family.
  
  
 
0.926
SPRI_1532
ATP-dependent helicase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.795
SPRI_2145
3-oxoacyl-ACP reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.758
SPRI_2142
AraC family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.737
SPRI_2140
Branched-chain amino acid transporter AzlD; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.734
SPRI_2141
Branched-chain amino acid ABC transporter permease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.734
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.585
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
     
 0.573
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
  
 0.564
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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