Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_2149Damage-inducible protein CinA; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (169 aa)    
Predicted Functional Partners:
nadD
Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.960
SPRI_5759
Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.940
SPRI_4633
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
 
 0.932
SPRI_2150
Phosphatidylglycerophosphate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
  
 0.922
SPRI_3401
Nicotinate-nucleotide pyrophosphorylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family.
     
 0.914
SPRI_4006
5'-nucleotidase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family.
  
 
  0.911
SPRI_2689
NUDIX hydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.908
SPRI_4694
Haloacid dehalogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the HAD-like hydrolase superfamily.
     
  0.900
rimO
Ribosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
  
  
 0.882
SPRI_2152
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.827
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.