Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_2182threonyl-tRNA synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (408 aa)    
Predicted Functional Partners:
pheT
phenylalanyl-tRNA synthetase subunit beta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
 
 0.926
thrS
threonyl-tRNA synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
  
 
0.908
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
 
 
 0.834
leuS
leucyl-tRNA synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.827
SPRI_5539
30S ribosomal protein S1; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.783
cysS
cysteinyl-tRNA synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.779
rsfS
Iojap superfamily protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
 0.779
SPRI_1512
methionyl-tRNA synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.774
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.757
rpmA
50S ribosomal protein L27; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL27 family.
  
 
 0.743
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (14%) [HD]