SPRI_2248 protein (Streptomyces pristinaespiralis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SPRI_2248

DNA-directed RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (278 aa)

Predicted Functional Partners:

SPRI_4030

0.983

SPRI_2155

0.879

whiA

0.879

SPRI_6079

0.868

SPRI_2169

0.834

SPRI_2247

0.820

SPRI_2249

0.729

SPRI_2250

0.724

SPRI_2251

0.724

rpoC

0.717

Your Current Organism:

Streptomyces pristinaespiralis

NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPRI_2155	SPRI_2247	SPRI_2155	SPRI_2247	Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	TetR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.404
SPRI_2155	SPRI_2248	SPRI_2155	SPRI_2248	Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	DNA-directed RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.879
SPRI_2155	SPRI_2249	SPRI_2155	SPRI_2249	Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit beta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.576
SPRI_2155	rpoC	SPRI_2155	SPRI_3200	Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Nos4; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.718
SPRI_2169	SPRI_2248	SPRI_2169	SPRI_2248	BldB protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	DNA-directed RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.834
SPRI_2169	SPRI_6079	SPRI_2169	SPRI_6079	BldB protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	XRE family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.811
SPRI_2169	whiA	SPRI_2169	SPRI_5580	BldB protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Sporulation protein; Involved in cell division and chromosome segregation.	0.469
SPRI_2247	SPRI_2155	SPRI_2247	SPRI_2155	TetR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.404
SPRI_2247	SPRI_2248	SPRI_2247	SPRI_2248	TetR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	DNA-directed RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.820
SPRI_2247	SPRI_2249	SPRI_2247	SPRI_2249	TetR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit beta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.683
SPRI_2247	SPRI_2250	SPRI_2247	SPRI_2250	TetR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Mg chelatase-like protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.681
SPRI_2247	SPRI_2251	SPRI_2247	SPRI_2251	TetR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	UPF0102 protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the UPF0102 family.	0.681
SPRI_2248	SPRI_2155	SPRI_2248	SPRI_2155	DNA-directed RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.879
SPRI_2248	SPRI_2169	SPRI_2248	SPRI_2169	DNA-directed RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	BldB protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.834
SPRI_2248	SPRI_2247	SPRI_2248	SPRI_2247	DNA-directed RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	TetR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.820
SPRI_2248	SPRI_2249	SPRI_2248	SPRI_2249	DNA-directed RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA polymerase III subunit beta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.729
SPRI_2248	SPRI_2250	SPRI_2248	SPRI_2250	DNA-directed RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Mg chelatase-like protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.724
SPRI_2248	SPRI_2251	SPRI_2248	SPRI_2251	DNA-directed RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	UPF0102 protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the UPF0102 family.	0.724
SPRI_2248	SPRI_4030	SPRI_2248	SPRI_4030	DNA-directed RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	AmfC protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.983
SPRI_2248	SPRI_6079	SPRI_2248	SPRI_6079	DNA-directed RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	XRE family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.868

page 1 of 3

Server load: low (22%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Textmining

Cooccurrence

Databases

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About