Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SPRI_2250Mg chelatase-like protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (541 aa)    
Predicted Functional Partners:
SPRI_2249
DNA polymerase III subunit beta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.976
SPRI_2251
UPF0102 protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the UPF0102 family.
 
  
 0.958
ruvC
Holliday junction DNA helicase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
 
   
 0.765
SPRI_2252
Protein often found in actinomycetes clustered with signal peptidase and/or RNaseHII; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.753
SPRI_2253
DNA mismatch repair protein MutT; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the Nudix hydrolase family.
  
    0.728
SPRI_2254
Signal peptidase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
       0.727
SPRI_2248
DNA-directed RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.708
SPRI_2255
Signal peptidase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
       0.680
SPRI_2256
Signal peptidase I; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
       0.680
SPRI_2257
Peptidase S26; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
       0.680
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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