STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_2286Cell division initiation protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (363 aa)    
Predicted Functional Partners:
SPRI_2288
Methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.838
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
       0.780
rpmF-2
50S ribosomal protein L32; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL32 family.
       0.746
SPRI_2285
Metal-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.746
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
       0.734
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
       0.733
mutM
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.668
SPRI_2292
Dihydroxyacetone kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.615
rpmB
50S ribosomal protein L28; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL28 family.
       0.555
SPRI_4944
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.453
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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