close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_2297Lipoprotein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (156 aa)    
Predicted Functional Partners:
SPRI_2296
AsnC family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.874
thiL
Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.732
SPRI_2294
Phosphomethylpyrimidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.730
SPRI_2817
Secreted protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.595
SPRI_5949
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.525
SPRI_4512
Glycosyl transferase family 2; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.524
SPRI_4462
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.522
SPRI_4127
DUF4031 domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.506
SPRI_2653
Metal-dependent phosphohydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.473
SPRI_3858
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.473
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.