STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_23122-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (257 aa)    
Predicted Functional Partners:
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
  
  
 0.906
SPRI_2313
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.764
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
  
  
 0.761
SPRI_2309
Hydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
   0.749
SPRI_2310
Cytosolic protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.593
argH
Argininosuccinate lyase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.507
fumC
Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 
 
 0.446
SPRI_2348
1-pyrroline-5-carboxylate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.422
c106_07c
Acyl carrier protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.402
SPRI_7104
Acyl carrier protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.402
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.