Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
SPRI_2419LuxR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (218 aa)    
Predicted Functional Partners:
SPRI_2420
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.961
SPRI_2155
Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.867
SPRI_2421
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.818
SPRI_2422
Sulfate ABC transporter ATPase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
    0.813
SPRI_6433
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   0.794
SPRI_5593
Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   0.793
SPRI_2224
Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   0.789
SPRI_0742
Two component transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   0.783
SPRI_1436
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.782
SPRI_4091
Nickel transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.782
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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