Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_2449Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (158 aa)    
Predicted Functional Partners:
SPRI_2448
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     0.982
SPRI_2450
Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.946
SPRI_2155
Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.927
SPRI_2044
Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.713
SPRI_1963
Response regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.683
SPRI_0301
Branched-chain alpha-keto acid decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.656
SPRI_7052
Branched-chain alpha-keto acid decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.656
SPRI_2599
Alpha-ketoglutarate decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.602
SPRI_2492
Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.591
SPRI_2447
PKD domain containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.589
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.