STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_2527Protein-tyrosine phosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (216 aa)    
Predicted Functional Partners:
SPRI_0976
Protein-tyrosine phosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.908
SPRI_5281
Protein-tyrosine phosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.908
SPRI_3833
Protein-tyrosine phosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
     
  0.900
SPRI_2528
Translation factor SUA5; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the SUA5 family.
       0.884
SPRI_6925
MBL fold metallo-hydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.812
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
    0.750
prmC
SAM-dependent methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
       0.688
rpmE
50S ribosomal protein L31; Binds the 23S rRNA.
       0.685
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
       0.617
SPRI_0724
Thioredoxin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.593
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.