Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_2563Aldehyde dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (505 aa)    
Predicted Functional Partners:
SPRI_2564
UDP-glucose 4-epimerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
    0.955
SPRI_1579
AMP-dependent synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.921
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.921
SPRI_0413
Molecular chaperone GroES; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.914
SPRI_5203
Molecular chaperone GroES; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.914
SPRI_5836
Alcohol dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.914
SPRI_1619
Pyruvate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family.
  
 0.912
SPRI_6631
Thiamine pyrophosphate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family.
  
 0.912
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.906
ackA-2
Hypothetical protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.906
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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