Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_2570ATP-dependent DNA ligase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (295 aa)    
Predicted Functional Partners:
SPRI_0779
3'-phosphoesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.990
ku
DNA repair protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.978
SPRI_1068
ATP-dependent DNA ligase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.974
SPRI_2571
DNA ligase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.974
SPRI_6912
ATP-dependent DNA ligase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 
0.922
ku-2
DNA repair protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.877
lig
ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
   
 0.798
SPRI_2572
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.598
SPRI_2573
PBS lyase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.464
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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