STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_2596Spermidine synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (231 aa)    
Predicted Functional Partners:
SPRI_2598
Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.799
SPRI_2597
Two-component system response regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.798
SPRI_2599
Alpha-ketoglutarate decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.708
lon
Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
    0.656
SPRI_2600
Putative membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.652
SPRI_2595
GCN5 family acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.638
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
    0.423
trmD
tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
   
    0.414
rimM
16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
   
    0.414
SPRI_4778
Agmatinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the arginase family.
  
  
 0.411
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.