Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_2654Metal-dependent phosphohydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (461 aa)    
Predicted Functional Partners:
SPRI_2359
Integral membrane phosphodiesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.907
SPRI_2653
Metal-dependent phosphohydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
0.901
SPRI_2155
Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.818
SPRI_2944
Diguanylate cyclase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.794
SPRI_2656
RNA polymerase sigma factor RpoE; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
   
   0.745
SPRI_2652
Tetratricopeptide repeat domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.738
SPRI_2655
Anti-sigma factor; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.729
SPRI_2657
Hydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.684
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
       0.682
SPRI_2378
Phosphodiesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.661
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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