Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_2698Molybdopterin biosynthesis protein MoeZ; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (392 aa)    
Predicted Functional Partners:
SPRI_4109
Molybdenum cofactor biosynthesis protein MoaD; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.988
SPRI_4638
Molybdenum cofactor biosynthesis protein MoaD; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.988
SPRI_2388
Cysteine desulfurase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.982
SPRI_5342
Aminotransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family.
   
 0.980
SPRI_4015
Thiamine biosynthesis protein ThiS; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.968
SPRI_2673
Molybdopterin biosynthesis protein MoeE; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.962
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.962
SPRI_5392
Thiamine biosynthesis protein ThiS; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.932
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.856
SPRI_2294
Phosphomethylpyrimidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.835
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (22%) [HD]