STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_2700Reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (319 aa)    
Predicted Functional Partners:
SPRI_2699
Phage-related protein, tail component; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.926
SPRI_0241
Putative NDP-hexose-4 ketoreductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 
0.921
SPRI_2702
Transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.898
SPRI_2698
Molybdopterin biosynthesis protein MoeZ; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.829
SPRI_2701
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.751
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
 0.747
rpsS
30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
  0.743
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
 0.735
rpsQ
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
 0.733
SPRI_1884
Phosphoheptose isomerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.729
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.