Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
SPRI_2722Magnesium transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (420 aa)    
Predicted Functional Partners:
SPRI_2723
Integral membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.966
SPRI_2724
ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.811
SPRI_2721
Lipoprotein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.752
SPRI_3402
Aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
 0.551
secD
Bifunctional preprotein translocase subunit SecD/SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
 
 0.512
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.467
SPRI_4221
Dihydrofolate reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
   
 0.431
secD-2
Protein-export membrane protein secD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 
   
 0.423
SPRI_2155
Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.421
secF
Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
  
 
 0.414
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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