Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_2745Crystallin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (121 aa)    
Predicted Functional Partners:
SPRI_0727
TIGR02452 family protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.762
pipA
Lysine cyclodeaminase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
      
 0.618
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
   
 0.590
SPRI_3499
Alanine dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.552
SPRI_5752
L-alanine dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the AlaDH/PNT family.
      
 0.541
SPRI_2746
Type IV secretion protein Rhs; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.499
SPRI_3675
Integral membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.466
kptA
Phosphotransferase KptA/Tpt1; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.
 
   
 0.455
SPRI_2268
Nitrogen regulatory protein P-II 1; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 
 0.450
SPRI_6262
DUF4343 domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.449
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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