Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_2790DNA methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (527 aa)    
Predicted Functional Partners:
SPRI_2791
Restriction modification system DNA specificity subunit; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.999
SPRI_2792
Type III restriction enzyme; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.986
SPRI_2793
ATP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.548
SPRI_2794
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.532
SPRI_4066
Restriction endonuclease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.469
SPRI_4437
Restriction endonuclease subunit M; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.448
SPRI_6791
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.444
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
   
 
 0.432
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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